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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Aspirantskiy Vestnik Povolzhiya</journal-id><journal-title-group><journal-title xml:lang="en">Aspirantskiy Vestnik Povolzhiya</journal-title><trans-title-group xml:lang="ru"><trans-title>Аспирантский вестник Поволжья</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2072-2354</issn><issn publication-format="electronic">2410-3764</issn><publisher><publisher-name xml:lang="en">Samara State Medical University</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">626990</article-id><article-id pub-id-type="doi">10.35693/AVP626990</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>OBSTETRICS AND GYNECOLOGY</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>АКУШЕРСТВО И ГИНЕКОЛОГИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Difficulties in differential diagnosis of preeclampsia and acute surgical pathology</article-title><trans-title-group xml:lang="ru"><trans-title>Сложности дифференциальной диагностики преэклампсии и острой хирургической патологии</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5879-418X</contrib-id><name-alternatives><name xml:lang="en"><surname>Kaganova</surname><given-names>Mariya A.</given-names></name><name xml:lang="ru"><surname>Каганова</surname><given-names>М. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD, Associate professor of the Department of Obstetrics and Gynecology of Institute of Postgraduate Education</p></bio><bio xml:lang="ru"><p>д-р мед. наук, доцент кафедры акушерства и гинекологии ИПО</p></bio><email>mkaganova@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3390-8034</contrib-id><name-alternatives><name xml:lang="en"><surname>Spiridonova</surname><given-names>Natalya V.</given-names></name><name xml:lang="ru"><surname>Спиридонова</surname><given-names>Н. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD, Professor, Head of the Department of Obstetrics and Gynecology of Institute of Postgraduate Education</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор, заведующая кафедрой акушерства и гинекологии ИПО</p></bio><email>nvspiridonova@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3248-5810</contrib-id><name-alternatives><name xml:lang="en"><surname>Artyukh</surname><given-names>Yuliya A.</given-names></name><name xml:lang="ru"><surname>Артюх</surname><given-names>Ю. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD, assistant of the Department of Obstetrics and Gynecology of Institute of Postgraduate Education</p></bio><bio xml:lang="ru"><p>канд. мед. наук, ассистент кафедры акушерства и гинекологии ИПО</p></bio><email>artyyuliya@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Denisova</surname><given-names>Natalya G.</given-names></name><name xml:lang="ru"><surname>Денисова</surname><given-names>Н. Г.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>PhD, Head of the 20th obstetric department</p></bio><bio xml:lang="ru"><p>канд. мед. наук, заведующая акушерским отделением №20</p></bio><email>denisov_a_nata@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Katkov</surname><given-names>Sergei S.</given-names></name><name xml:lang="ru"><surname>Катков</surname><given-names>С. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Head of the 7th surgical department</p></bio><bio xml:lang="ru"><p>заведующий хирургическим отделением №7</p></bio><email>Sskat1982@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Antropov</surname><given-names>Igor V.</given-names></name><name xml:lang="ru"><surname>Антропов</surname><given-names>И. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Head of the 6th surgical department</p></bio><bio xml:lang="ru"><p>заведующий хирургическим отделением №6</p></bio><email>a1973iv@yandex.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0137-5045</contrib-id><name-alternatives><name xml:lang="en"><surname>Yakovleva</surname><given-names>Mariya A.</given-names></name><name xml:lang="ru"><surname>Яковлева</surname><given-names>М. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>resident of the Department of Obstetrics and Gynecology of the Institute of Postgraduate Education</p></bio><bio xml:lang="ru"><p>ординатор кафедры акушерства и гинекологии ИПО</p></bio><email>mariayakovleva99@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Samara State Medical University</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Самарский государственный медицинский университет» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Samara City Clinical Hospital № 1 named after N.I. Pirogov</institution></aff><aff><institution xml:lang="ru">ГБУЗ Самарской области «Самарская городская клиническая больница №1 имени Н.И. Пирогова»</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2024-11-10" publication-format="electronic"><day>10</day><month>11</month><year>2024</year></pub-date><pub-date date-type="pub" iso-8601-date="2024-12-08" publication-format="electronic"><day>08</day><month>12</month><year>2024</year></pub-date><volume>24</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>4</fpage><lpage>10</lpage><history><date date-type="received" iso-8601-date="2024-02-15"><day>15</day><month>02</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2024-09-19"><day>19</day><month>09</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Kaganova M.A., Spiridonova N.V., Artyukh Y.A., Denisova N.G., Katkov S.S., Antropov I.V., Yakovleva M.A.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, Каганова М.А., Спиридонова Н.В., Артюх Ю.А., Денисова Н.Г., Катков С.С., Антропов И.В., Яковлева М.А.</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Kaganova M.A., Spiridonova N.V., Artyukh Y.A., Denisova N.G., Katkov S.S., Antropov I.V., Yakovleva M.A.</copyright-holder><copyright-holder xml:lang="ru">Каганова М.А., Спиридонова Н.В., Артюх Ю.А., Денисова Н.Г., Катков С.С., Антропов И.В., Яковлева М.А.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://aspvestnik.ru/2410-3764/article/view/626990">https://aspvestnik.ru/2410-3764/article/view/626990</self-uri><abstract xml:lang="en"><p><bold>Aim </bold>– to determine the prevalence of preeclampsia and HELLP syndrome among patients hospitalized in surgical departments with complaints of pain in the epigastrium, right hypochondrium and/or nausea and vomiting.</p> <p><bold>Material and methods. </bold>An analysis was carried out of visits of pregnant women over 20 weeks to the surgical department in 2023 and 42 cases of hospitalization of pregnant patients with suspected acute surgical pathology hospitalized in surgical departments No. 6 and No. 7 of the Samara City Clinical Hospital No. 1 named after N.I. Pirogov. The following parameters were assessed: age, gestational age, complaints at the time of admission, general blood and urine test data, the condition of the fetus according to ultrasound, Doppler ultrasound, CTG, presence of obstetric and gynecological pathology and somatic diseases.</p> <p><bold>Results. </bold>Patients with acute appendicitis (7 out of 42 pregnant women) were excluded from the study. Of the remaining 35 patients, the diagnosis of severe preeclampsia, HELLP syndrome was made in 3 cases (8.6%), in 2 cases, gestational hypertension or protineria (5.7%) – the main group. Cholelithiasis, acute cholecystitis – in 2 cases (5.7%), in other cases the diagnosis of acute pancreatitis was made – 28 patients (80.0%). The work provides a comparison of clinical and laboratory parameters of patients in two groups, with obstetric and surgical pathology. A clinical case of a combination of severe PE with the development of HELLP-syndrome and cholecystitis is also presented.</p> <p><bold>Conclusions.</bold> Differential diagnosis between obstetric complications such as PE and HELLP-syndrome and acute surgical pathology still remains a pressing interdisciplinary problem. Severe forms of PE can take the form of acute pancreatitis, acute cholecystitis, or other diseases. According to the results of our observation, this phenomenon occurred in 15% of patients hospitalized in surgical departments. Only timely diagnosis allows choosing adequate routing and specialized care for this complication.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Цель</bold> – определить распространенность и особенности диагностики преэклампсии и HELLP-синдрома среди пациенток, госпитализируемых в хирургические отделения с жалобами на боли в эпигастрии, правом подреберье и/или тошноту, рвоту.</p> <p><bold>Материал и методы.</bold> Проведен анализ обращений беременных в сроке свыше 20 недель в хирургическое отделение за 2023 год и 42 случаев госпитализации беременных пациенток с подозрением на острую хирургическую патологию в хирургические отделения №6 и №7 ГБУЗ «Самарская городская клиническая больница №1 имени Н.И. Пирогова». Оценивались такие параметры, как возраст, срок беременности, жалобы на момент поступления, данные лабораторных методов исследования, состояние плода по данным УЗИ, УЗДГ, КТГ, наличие акушерской и гинекологической патологии и соматических заболеваний.</p> <p><bold>Результаты.</bold> Из исследования были исключены пациентки с острым аппендицитом (7 из 42 беременных). Из оставшихся 35 пациенток диагноз тяжелой преэклампсии, HELLP-синдрома был выставлен в 3 случаях (8,6%), в 2 случаях гестационная артериальная гипертензия или протеинурия (5,7%) – основная группа. Желчнокаменная болезнь (ЖКБ), острый холецистит – в 2 случаях (5,7%), в остальных случаях был выставлен диагноз острого панкреатита – 28 пациенток (80,0%). В работе приведено сравнение клинико-лабораторных параметров пациенток двух групп: с акушерской и с хирургической патологией. Также приведен клинический случай сочетания тяжелой ПЭ с развитием HELLP-синдрома на фоне ЖКБ.</p> <p><bold>Выводы. </bold>Дифференциальная диагностика между ПЭ в сочетании с HELLP-синдромом и острой хирургической патологией до сих пор остается актуальной междисциплинарной проблемой. Тяжелые формы ПЭ могут принимать маски острого панкреатита, острого холецистита и других заболеваний. По результатам нашего наблюдения, это явление встречалось у 15% пациенток, госпитализированных в хирургические отделения, и только своевременная диагностика позволяет выбрать адекватную маршрутизацию и оказать специализированную помощь при данном осложнении.</p></trans-abstract><kwd-group xml:lang="en"><kwd>preeclampsia</kwd><kwd>HELLP-syndrome</kwd><kwd>acute pancreatitis</kwd><kwd>acute cholecystitis</kwd><kwd>pregnancy complications</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>преэклампсия</kwd><kwd>HELLP-синдром</kwd><kwd>острый панкреатит</kwd><kwd>острый холецистит</kwd><kwd>осложнения беременности</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Gestational Hypertension and Preeclampsia: ACOG Practice Bulletin Summary, Number 222. Obstet Gynecol. 2020;135(6):1492-1495. 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