Three-component synthesis of new C3-substituted 5,6-dihydropyrrolo[2,1-a]isoquinolines

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Abstract

New C3-substituted 5,6-dihydropyrrolo[2,1- a ]isoquinolines were obtained by a three-component domino reaction of 1-aroyl-3,4-dihydroisoquinolines, dimethylacetylenedicarboxylate, and CH-acids. The transformations proceed under microwave irradiation at 130°C in dry acetonitrile.

About the authors

A. R. Miftyakhova

Peoples’ Friendship University of Russia (RUDN University)

Email: almira244@gmail.com

M. B. Sidakov

Peoples’ Friendship University of Russia (RUDN University)

T. N. Borisova

Peoples’ Friendship University of Russia (RUDN University)

A. N. Fakhrutdinov

N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences

A. A. Titov

Peoples’ Friendship University of Russia (RUDN University)

E. A. Sorokina

Peoples’ Friendship University of Russia (RUDN University)

A. V. Varlamov

Peoples’ Friendship University of Russia (RUDN University)

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