Pecularities of 16-nitro- and 16-amino-14,17-ethanosteroids preparation in the estrane series

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Abstract

The hydrogenation of 16-nitro-14,17-ethenosteroids over various catalysts was studied, chemoselectivity criteria have been established, new bridged estradiol analogs bearing nitro, amino and hydroxylamino groups in the D ring have been prepared. A complete assignment of signals in the NMR spectra of the synthesized products was fulfilled

About the authors

A. V Baranovsky

Institute of bioorganic chemistry of the National Academy of Sciences

Email: baranovsky@iboch.by

A. S Ladyko

Institute of bioorganic chemistry of the National Academy of Sciences

S. N Sokolov

Institute of bioorganic chemistry of the National Academy of Sciences

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