One-pot synthesis of N-acylethenyl4-acylethenyliminodihydroquinolines from 4-aminoquinoline and alkynones

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Abstract

One-pot chemo-, regio- and stereoselective synthesis of ( Z )- N -acylethenyl-4-( E )-[( Z )-acylethenyl]iminodihydroquinolines with high yields (66-98%) has been elaborated by the reaction between 4-aminoqiunoline and alkynones in the КОН/H2O/MeCN system.

About the authors

L. P Nikitina

A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences

Email: boris_trofimov@irioch.irk.ru

K. V Belyaeva

A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences

Email: boris_trofimov@irioch.irk.ru

A. V Afonin

A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences

Email: boris_trofimov@irioch.irk.ru

I. A Ushakov

A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences

Email: boris_trofimov@irioch.irk.ru

B. A Trofimov

A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences

Email: boris_trofimov@irioch.irk.ru

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