Synthesis of Spiro[indole-3,2′-pyrrole]triones by the Reaction of Pyrrolobenzoxazepinetriones with Enaminoketone
- Authors: Maslivets A.A.1, Dmitriev M.V.1, Maslivets A.N.1
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Affiliations:
- Perm State University
- Issue: Vol 60, No 2-3 (2024)
- Pages: 162–166
- Section: Articles
- URL: https://aspvestnik.ru/0514-7492/article/view/672198
- DOI: https://doi.org/10.31857/S0514749224020033
- EDN: https://elibrary.ru/EKHZXE
- ID: 672198
Cite item
Abstract
The reaction of 3-aroylpyrrolo[1,2-a][4,1]benzoxazepin-1,2,4-triones with 3-cyclohexylamino-5,5-dimethylcyclohex-2-en-1-one leads to the formation of 3′-(4-aroyl)-4′-hydroxy-1′-(2-(hydroxymethyl)phenyl)-6,6-dimethyl-1-cyclohexyl-6,7-dihydrospiro[indole-3,2′-pyrrole]-2,4,5′(1H,1′H,5H)-triones. A new scheme for the interaction of 3-aroylpyrrolo[1,2-а][4,1]benzoxazepine-1,2,4-triones with N-substituted enaminoketones leading to the formation of derivatives of the difficult-to-reach heterocyclic systems of spiro[indole-3,2′-pyrrole]triones is described.
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About the authors
A. A. Maslivets
Perm State University
Email: koh2@psu.ru
ORCID iD: 0000-0003-0555-0231
Russian Federation, ul. Bukireva, 15, Perm, 614990
M. V. Dmitriev
Perm State University
Email: koh2@psu.ru
ORCID iD: 0000-0002-8817-0543
Russian Federation, ul. Bukireva, 15, Perm, 614990
A. N. Maslivets
Perm State University
Author for correspondence.
Email: koh2@psu.ru
ORCID iD: 0000-0001-7148-4450
Russian Federation, ul. Bukireva, 15, Perm, 614990
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