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Cp2ZrCl2-EtMgBr-Catalysed Reaction of 2-Zincoethylzincation of 2-Alkynylamines
- Authors: Gabdullin A.M.1, Kadikova R.N.1, Ramazanov I.R.1
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Affiliations:
- Institute of Petrochemistry and Catalysis, Ufa Federal Research Center, Russian Academy of Sciences
- Issue: Vol 60, No 1 (2024)
- Pages: 68-74
- Section: Articles
- URL: https://aspvestnik.ru/0514-7492/article/view/672226
- DOI: https://doi.org/10.31857/S0514749224010056
- EDN: https://elibrary.ru/ENKQWW
- ID: 672226
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Abstract
It was found that the Cp2ZrCl2-EtMgBr-catalyzed reaction of 2-alkynylamines with Et2Zn leads to the regio- and stereoselective formation of (2Z)-allylamines in high yield. It has been established that the presence of morpholyl and piperidyl substituents in the structure of propargylamines does not interfere with the regio- and stereoselective 2-zincoethylzincation of the triple bond. Carbocyclization of α,ω-bis(aminomethyl)alkadiynes based on the Cp2ZrCl2-EtMgBr-catalyzed carbozincation reaction with Et2Zn was carried out for the first time. A mechanism for the catalytic 2-zincoethylzincation of α,ω-bis(aminomethyl)alkadiynes was proposed.
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About the authors
A. M. Gabdullin
Institute of Petrochemistry and Catalysis, Ufa Federal Research Center, Russian Academy of Sciences
Author for correspondence.
Email: kadikritan@gmail.com
ORCID iD: 0000-0001-5204-7394
Russian Federation, Ufa
R. N. Kadikova
Institute of Petrochemistry and Catalysis, Ufa Federal Research Center, Russian Academy of Sciences
Email: kadikritan@gmail.com
ORCID iD: 0000-0002-4636-1739
Russian Federation, Ufa
I. R. Ramazanov
Institute of Petrochemistry and Catalysis, Ufa Federal Research Center, Russian Academy of Sciences
Email: kadikritan@gmail.com
ORCID iD: 0000-0002-3846-6581
Russian Federation, Ufa
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