Synthesis, spectral, electrochemical properties, antioxidant and antiviral activity of new 2-[5-phenyl-6-methyl-3-aryl/getaryl-5,6-dihydro-4h-[1,2,4,5]tetrazine-1-yl]-benzothiazoles

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Abstract

New 2-[5-aryl-6-methyl-3-aryl/getaryl-5,6-dihydro-4H-[1,2,4,5]tetrazine-1-yl]-benzothiazole has been synthesized from the corresponding formazanes by alkylation and subsequent cyclization of N-alkyl derivatives. The products are characterized by 1H, 13C NMR, IR, spectroscopy, mass spectrometry and X-ray diffraction analysis. The electrochemical properties, antioxidant and antiviral activity of the obtained benzothiazoles were studied.

About the authors

T. G. Fedorchenko

Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences

Author for correspondence.
Email: flumd@mail.ru
Russian Federation, ul. S. Kovalevskoi, 22/20, Yekaterinburg 620108

G. N. Lipunova

Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences

Email: flumd@mail.ru
Russian Federation, ul. S. Kovalevskoi, 22/20, Yekaterinburg 620108

A. S. Volobueva

St. Petersburg Pasteur Institute

Email: flumd@mail.ru
Russian Federation, 197101, St. Petersburg, Mira str., 14

V. V. Zarubaev

St. Petersburg Pasteur Institute

Email: flumd@mail.ru
Russian Federation, 197101, St. Petersburg, Mira str., 14

M. S. Valova

Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences

Email: flumd@mail.ru
Russian Federation, ul. S. Kovalevskoi, 22/20, Yekaterinburg 620108

A. V. Shchepochkin

Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural Federal named after the first President of Russia B. N. Yeltsin

Email: flumd@mail.ru
Russian Federation, ul. S. Kovalevskoi, 22/20, Yekaterinburg 620108; ul. Mira, 19, Yekaterinburg, 620002

M. A. Averkov

Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural Federal named after the first President of Russia B. N. Yeltsin

Email: flumd@mail.ru
Russian Federation, ul. S. Kovalevskoi, 22/20, Yekaterinburg 620108; ul. Mira, 19, Yekaterinburg, 620002

V. N. Tungusov

Ural Federal named after the first President of Russia B. N. Yeltsin

Email: flumd@mail.ru
Russian Federation, ul. Mira, 19, Yekaterinburg, 620002

P. A. Slepukhin

Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural Federal named after the first President of Russia B. N. Yeltsin

Email: flumd@mail.ru
Russian Federation, ul. S. Kovalevskoi, 22/20, Yekaterinburg 620108; ul. Mira, 19, Yekaterinburg, 620002

O. N. Chupakhin

Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences; Ural Federal named after the first President of Russia B. N. Yeltsin

Email: flumd@mail.ru
Russian Federation, ul. S. Kovalevskoi, 22/20, Yekaterinburg 620108; ul. Mira, 19, Yekaterinburg, 620002

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