Interaction of 5-Hydroxypyrazolidine with Thiol-Containing Hydrazides as a Method of Synthesis of Biologically Active Ligands of Gold Glyco-Nanoparticles

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The interaction of (3S)-1-acetyl-5-hydroxy-2-phenyl-3-methylpyrazolidine with 6-mercaptohexanoic and 11-mercaptoundecanoic acid hydrazides leads to the formation in 60–65% yields of (3S)-1-acetyl-5-[(ω-mercaptoacyl)hydrazine]-2-phenyl-3-methylpyrazolidines as a promising сo-ligands for the production of gold glyco-nanoparticles for biomedical purposes.

作者简介

A. Ershov

Institute of Macromolecular Compounds of the Russian Academy of Sciences

Email: martynenkoff@gmail.com
ORCID iD: 0000-0002-2266-4380
俄罗斯联邦, Bol′shoi prosp., 31, St. Petersburg, 199004

A. Martynenkov

Institute of Macromolecular Compounds of the Russian Academy of Sciences

编辑信件的主要联系方式.
Email: martynenkoff@gmail.com
ORCID iD: 0000-0002-0951-1451
俄罗斯联邦, Bol′shoi prosp., 31, St. Petersburg, 199004

I. Lagoda

State Research Testing Institute of Military Medicine, Ministry of Defense of the Russian Federation

Email: martynenkoff@gmail.com
ORCID iD: 0000-0002-3906-2909
俄罗斯联邦, Lesoparkovaya ul., 4, St. Petersburg, 195043

A. Batyrenko

State Research Testing Institute of Military Medicine, Ministry of Defense of the Russian Federation

Email: martynenkoff@gmail.com
ORCID iD: 0000-0001-9688-3650
俄罗斯联邦, Lesoparkovaya ul., 4, St. Petersburg, 195043

参考

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