Application of the ANRORC-Process for the Directional Synthesis of 5-Ureido-2-Pyrazolines as a Biologically Active Co-Ligand of Gold Glyconanoparticles

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Дәйексөз келтіру

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Аннотация

Interaction of 1-phenyl-4,6-dimethylpyrimidine-2(1H)-one with 4-mercaptobuturic acid hydrazide proceeds as ANRORC (Addition of the Nucleophile–Ring Opening–Ring Closure) process and gives in the formation with 60% yield of 1-(4-mercaptobutanoyl)-3,5-dimethyl-5-(3-phenylcarbamoylamino)-2-pyrazoline as promising сo-ligand for the preparation of gold glyconanoparticles for biomedical purposes.

Негізгі сөздер

Авторлар туралы

A. Ershov

Institute of Macromolecular Compounds of the Russian Academy of Sciences

Email: martynenkoff@gmail.com
ORCID iD: 0000-0002-2266-4380
Ресей, Bol′shoi prosp., 31, St. Petersburg, 199004

A. Martynenkov

Institute of Macromolecular Compounds of the Russian Academy of Sciences

Хат алмасуға жауапты Автор.
Email: martynenkoff@gmail.com
ORCID iD: 0000-0002-0951-1451
Ресей, Bol′shoi prosp., 31, St. Petersburg, 199004

I. Lagoda

State Research Testing Institute of Military Medicine, Ministry of Defense of the Russian Federation

Email: martynenkoff@gmail.com
ORCID iD: 0000-0002-3906-2909
Ресей, Lesoparkovaya ul., 4, St. Petersburg, 195043

A. Batyrenko

State Research Testing Institute of Military Medicine, Ministry of Defense of the Russian Federation

Email: martynenkoff@gmail.com
ORCID iD: 0000-0001-9688-3650
Ресей, Lesoparkovaya ul., 4, St. Petersburg, 195043

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