Functionalization of 4-hydroxy-6-methyl-2Н-pyran-2-one under the conditions of the modified Biginelli reaction

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The features of the interaction of 4-hydroxy-6-methyl-2 H -pyran-2-one with aromatic aldehydes and urea in the one-pot mode of the classical mode, as well as using thermal and microwave activation of The Biginelli reaction variants, were studied. Depending on the conditions of single-reactory processes, previously unknown 3-[amino(aryl)methyl]-4-hydroxy-6-methyl-2 H -pyran-2-one, arylmethylenebis-4-hydroxy-6-methyl-2 H -pyran2-one, hybrid system - 2-hydroxy-7-methyl-4-(3-nitrophenyl)-4,4a-dihydro-5 H -pyrano[4,3- d ]pyrimidine-5-one in the case of transformation with aryl aldehyde containing an electron-acceptor substitute.

作者简介

I. Kanevskaya

Saratov State University

Email: irinastrashilina@mail.ru

N. Pchelintseva

Saratov State University

Email: irinastrashilina@mail.ru

O. Fedotova

Saratov State University

Email: irinastrashilina@mail.ru

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