Enviar artigo por via de e-mail Functionalization of 4-hydroxy-6-methyl-2Н-pyran-2-one under the conditions of the modified Biginelli reaction
- Autores: Kanevskaya I.V1, Pchelintseva N.V1, Fedotova O.V1
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Afiliações:
- Saratov State University
- Edição: Volume 59, Nº 4 (2023)
- Páginas: 466-474
- Seção: Articles
- URL: https://aspvestnik.ru/0514-7492/article/view/666309
- DOI: https://doi.org/10.31857/S0514749223040055
- EDN: https://elibrary.ru/ARIOMH
- ID: 666309
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Resumo
The features of the interaction of 4-hydroxy-6-methyl-2 H -pyran-2-one with aromatic aldehydes and urea in the one-pot mode of the classical mode, as well as using thermal and microwave activation of The Biginelli reaction variants, were studied. Depending on the conditions of single-reactory processes, previously unknown 3-[amino(aryl)methyl]-4-hydroxy-6-methyl-2 H -pyran-2-one, arylmethylenebis-4-hydroxy-6-methyl-2 H -pyran2-one, hybrid system - 2-hydroxy-7-methyl-4-(3-nitrophenyl)-4,4a-dihydro-5 H -pyrano[4,3- d ]pyrimidine-5-one in the case of transformation with aryl aldehyde containing an electron-acceptor substitute.
Palavras-chave
three-component condensation, thermal and microwave activation, 4-Hydroxy-6-methyl-2H-pyran-2-one, aromatic aldehydes, urea, 3-[amino(aryl)-methyl]-4-hydroxy-6-methyl-2H-pyran-2-one, arylmethylenebis4-hydroxy-6-methyl-2H-pyran-2-one, 2-hydroxy-7-methyl-4-(3-nitrophenyl)-4,4a-dihydro-5H-pyrano[4,3-d]pyrimidine-5-one, NMR spectra
Sobre autores
I. Kanevskaya
Saratov State University
Email: irinastrashilina@mail.ru
N. Pchelintseva
Saratov State University
Email: irinastrashilina@mail.ru
O. Fedotova
Saratov State University
Email: irinastrashilina@mail.ru
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